Shaw

RBP TDP-43 抑制了神经退行性疾病 FTD-ALS 中基因 UNC13A 的 cryptic exon(CE) 的保留TDP-43 represses cryptic exon inclusion in the FTD–ALS ge

2022-02-26 paper

RBP

Intron 的不同命运Differential fates of introns in gene expression due to globalalternative splicing 这篇 review 主要介绍了 intron

2022-02-25 paper

intron

CLIP-seq 中鉴定出的 circRNA-binding eventsHCRNet:high-throughputcircRNA-bindingeventidentificationfromCLIP-seqdatausingdeepte

2022-02-23 paper

CLIP RBP circRNA

原文：Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated

2022-02-22 paper

RBP microexon

awk命令作为 Linux 的三驾马车之一，功能强大，却也颇有些门道，之前对 awk 的认识仅仅能够满足基本操作需求，这里系统地重新学习一下 awk

2022-02-22 linux

cmd awk

global screening 鉴定出染色质富集的 RBP 和在单核细胞分化过程中 QKI5 的转录调节活性A global screening identifies chromatin-enriched RNA-binding pro

2022-02-20 paper

RBP Che-RBP

对环形化的外显子剪接位点进行碱基编辑，可以达到敲除 circRNA 的效果Knockout of circRNAs by base editing back-splice sites of circularized exons 杂志: Ge

2022-02-19 paper

circRNA

组蛋白修饰通过影响选择性剪接调节 EMT(epithelial-to-mesenchymal transition)Histone marks regulate the epithelial-to-mesenchymal transitio

2022-02-18 paper

histone modification

金字塔图金字塔图有几种方法/包绘制： plotrix 包 DescTools 包 PlotPyramid ggplot2 包 library(ggplot2) library(DescTools) library(plotrix) 使

2022-02-17 R数据可视化手册

R ggplot2

RNA pairing 阻止了“先来先服务”的剪接原则，促进了果蝇中 Dscam1 多种转录本的产生Hidden RNA pairings counteract the “first-come, first-served” splicing

2022-02-17 paper

RNA secondary structure

PC 病人中细胞循环相关基因的综合分析Comprehensive Analysis of Cell Cycle-Related Genes in Patients With Prostate Cancer 杂志: Fro In Onco(F

2022-02-16 paper

tumor

flies 和 mammals 中微外显子及其调节的比较，进化关联Parallel evolution of a splicing program controlling neuronal excitability in flies and

2022-02-15 paper

microexon SRRM3 SRRM4