statistics-1


下面有一段摘自于一篇 cell paper 的 Statistical analysis of biological data:

All results are presented as the mean with SD unless notified specifically. Statistics were assessed using a Mann-Whitney U-test [motif enrichment], two tailed student t-test or Welch’s t-test [general comparison], Audic and Claverie test [intron retention analysis], Fisher’s exact adjusted by Benjamini/Hochberg [gene overlap]. All the GO analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis were performed with Enrichr and all the adjusted p-values for GO analysis were exported from Enrichr. Markers of significance are as follows: #, p > 0.05; ∗, 0.01 < p ≤ 0.05; ∗∗, 0.001 < p ≤ 0.01; ∗∗∗, p ≤ 0.001.

source: Cell, 2023, Glucose dissociates DDX21 dimers to regulate mRNA splicing and tissue differentiation

其中涉及到了大部分生信统计中的常用方法,但截至到目前我还没有搞清楚,在什么情况下,该用什么统计方法,所以,系统学习一下统计学是非常必要的(天,感觉什么都要学)。

从这一部分开始,填充统计学方法。

SPSS

作为经典的统计学软件,在学习统计学理论知识的同时,不妨在 SPSS 上进行实操,理论+实践。


文章作者: 梁绍波
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