基因组范围的 CRISPR-Cas9 对剪接网络的研究揭示了与自闭症相关的 microexon 识别

原文：Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons

杂志：Mol Cell(Molecular Cell)

microexon splicing reporters：to evaluate impact
（which microexons to choose）

disrupt target genes
(how to determine which target genes: targeting 19,764 coding genes)

negative and positive impact of target genes on microexon reporter
（group for these regulators）